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Microglial methylation 'landscape' in human brain Posted: 28 Dec 2021 10:58 AM PST Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states. But the molecular mechanisms that contribute to these transcriptomic changes in the human brain are not well understood. Now, a new study targets the methylation profile of microglia from human brain.

Researchers develop structural blueprint of nanoparticles to target white blood cells responsible for acute lung inflammation Posted: 27 Dec 2021 12:44 PM PST A potential new route to the diagnosis and treatment of ARDS comes from studying how neutrophils -- the white blood cells responsible for detecting and eliminating harmful particles in the body -- differentiate what materials to uptake by the material's surface structure, and favor uptake of particles that exhibit 'protein clumping,' according to new research.

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